• １．Improvement of glucose spike (postprandial hyperglycemia ) can not be sufficiently detected by HbA1c or glycoalbumin (fructosamine)
• ２．Why only 1,5-anhydroglucitol(1,5-AG) can detect glucose spike?
• ３．Measuring 1,5-AG weekly, monthly, even yearly is effective in management of diabetes mellitus
• ４．1,5-AG of less than 14 μg/ml indicates existence of glucose spike even in near-normoglycemia
• ５．Rapid and wide variations of 1,5-AG make your clinical decision robust
• ６．Follow up on development of hyperglycemia in subjects with impaired glucose tolerance (IGT)
• ７．"Your glycemia is stable" → No!!
• ８．The value of approximate mean postmeal maximum plasma glucose levels corresponding to 1,5-AG
• ９．Hypoglycemia and 1,5-AG
• １０．Combination measurement with 1,5-AG and HbA1c
• １１．Factors that cause an abnormal value
• １２．What is 1,5-Anhydroglucitol (1,5-AG ) ?
• １３．Physiological role
• １４．1,5-AG and diabetic complications

７．"Your glycemia is stable" → No!!

  In this diabetic case, it has been stable not glucose but HbA1ｃ. Excursion of 1,5-AG suggests strongly unstable glycemia.

  HbA1c exhibits small change width. Based on the data of HbA1c, we are often misled that glycemia is very stable.

  Glycemia usually fluctuates intensely in patients with diabetics.

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